Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 13/20 | 0.74 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.74 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.74 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.68 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.63 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.59 |
| ▸ | FADS1 | O60427 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264405 | 0.88 | P2RX1 (0.72) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL11932152 | 0.86 | P2RX1 (1.00) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL29951220 | 0.85 | KMT2A (0.62) | P2RX1P2RX4P2RX7 | |
| SCHEMBL24438622 | 0.85 | P2RX1 (0.77) | P2RX1P2RX4P2RX7TMPRSS4KCNMA1 | |
| SCHEMBL538439 | 0.81 | TMPRSS4 (1.00) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL11932156 | 0.81 | P2RX1 (0.78) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL3860231 | 0.81 | P2RX1 (0.78) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL11932151 | 0.81 | P2RX1 (0.78) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL13812565 | 0.81 | P2RX1 (0.78) | P2RX1P2RX4P2RX7TMPRSS4SLC2A1 | |
| SCHEMBL2106756 | 0.80 | L3MBTL1 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109148-A1 | SMALL MOLECULE INHIBITORS OF SARS-COV-2 INFECTIONS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-05-27 | — | — | WO | disclosed |