Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439225 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL24438722 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL29674586 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL24440143 | 0.84 | ALDH1A1 (0.50) | ALDH1A1GAAPOLBNPSR1MEN1 | |
| SCHEMBL29674654 | 0.84 | ALDH1A1 (0.50) | ALDH1A1GAAPOLBNPSR1KDM4E | |
| SCHEMBL29674721 | 0.83 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBNPSR1ADORA2A | |
| SCHEMBL24438686 | 0.83 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBNPSR1ADORA2A | |
| SCHEMBL24439231 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GAAPOLBNPSR1PDE4A | |
| SCHEMBL24438663 | 0.80 | ALDH1A1 (0.43) | ALDH1A1GAAPOLBNPSR1LMNA | |
| SCHEMBL29603521 | 0.78 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103280-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LTD (NZ) | 2022-05-19 | — | — | WO | disclosed |