Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24438663 | 0.87 | ALDH1A1 (0.43) | ALDH1A1GAASRCNPSR1POLB | |
| SCHEMBL29674654 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAASRCNPSR1POLB | |
| SCHEMBL24438686 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAANPSR1CYP1A2POLB | |
| SCHEMBL29674721 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAANPSR1CYP1A2POLB | |
| SCHEMBL24439013 | 0.83 | ALDH1A1 (0.45) | ALDH1A1GAANPSR1POLBPDE4A | |
| SCHEMBL24439214 | 0.82 | ALDH1A1 (0.35) | ALDH1A1GAASRCCYP1A2LMNA | |
| SCHEMBL24439007 | 0.81 | ALDH1A1 (0.42) | ALDH1A1GAASRCNPSR1POLB | |
| SCHEMBL24438864 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAANPSR1POLBCA12 | |
| SCHEMBL24438661 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAASRCNPSR1CYP1A2 | |
| SCHEMBL29674660 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAANPSR1POLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103280-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LTD (NZ) | 2022-05-19 | — | — | WO | disclosed |