Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439346 | 0.81 | MAOB (0.41) | KMT2AMEN1CYP3A4TSHRKIF11 | |
| SCHEMBL17577314 | 0.79 | HTR2A (0.43) | ACHEARHTR2ASLC6A4KCNH2 | |
| SCHEMBL9616097 | 0.77 | TSHR (0.34) | KMT2AMEN1NPSR1TSHRKIF11 | |
| SCHEMBL27387713 | 0.77 | ACHE (0.55) | ACHEKMT2AMEN1CA1CA2 | |
| SCHEMBL130635 | 0.77 | ACHE (0.55) | ACHEKMT2AMEN1CA1CA2 | |
| SCHEMBL2149793 | 0.76 | ACHE (0.41) | ACHEKMT2AMEN1CA1CA2 | |
| SCHEMBL28421629 | 0.76 | ALDH1A1 (0.45) | KMT2AMEN1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL4809479 | 0.75 | ACHE (0.52) | ACHEKMT2AMEN1CA1CA2 | |
| SCHEMBL8650801 | 0.75 | ACHE (0.52) | ACHEKMT2AMEN1CA1CA2 | |
| SCHEMBL7771299 | 0.75 | ACHE (0.52) | ACHEKMT2AMEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103990-A1 | METHODS OF MODIFYING PHOSPHORYLATED OR SULFATED TYROSINE RESIDUES OF POLYPEPTIDES | PHOSFISH LLC (US) | 2022-05-19 | — | — | WO | disclosed |