Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 5/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27106121 | 0.84 | DYRK1A (0.47) | DYRK1ASTK17BSTK17ATDP1HTT | |
| SCHEMBL25056480 | 0.76 | HTT (0.44) | DYRK1ASTK17BSTK17ATDP1HTT | |
| SCHEMBL13712849 | 0.73 | TDP1 (0.54) | TDP1DRD2MEN1KMT2AGAA | |
| SCHEMBL7499604 | 0.71 | STING1 (0.49) | DYRK1ABRD4STING1 | |
| SCHEMBL22366404 | 0.71 | TDP1 (0.46) | DYRK1ASTK17BSTK17ATDP1HTT | |
| SCHEMBL19027343 | 0.70 | TLR8 (0.48) | DYRK1ASTK17BSTK17ATDP1DRD2 | |
| SCHEMBL19027921 | 0.70 | CA1 (0.44) | DYRK1ASTK17BSTK17ATDP1DRD2 | |
| SCHEMBL22012670 | 0.69 | TDP1 (0.47) | STK17BSTK17ATDP1DRD2MEN1 | |
| SCHEMBL21069415 | 0.69 | TDP1 (0.47) | DYRK1ASTK17BSTK17ATDP1DRD2 | |
| SCHEMBL27067055 | 0.69 | STK17B (0.45) | DYRK1ASTK17BSTK17ATDP1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022104206-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2022-05-19 | — | — | WO | disclosed |