Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401643 | 0.94 | TDP1 (0.41) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL13975444 | 0.92 | LMNA (0.47) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL22012670 | 0.88 | TDP1 (0.47) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL19027486 | 0.86 | DRD2 (0.45) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL31627058 | 0.86 | TDP1 (0.44) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL16245608 | 0.86 | TDP1 (0.44) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL20140741 | 0.85 | L3MBTL1 (0.52) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL13165704 | 0.85 | MEN1 (0.45) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL23513095 | 0.84 | TDP1 (0.43) | TDP1STK17BSTK17AMEN1GAA | |
| SCHEMBL23513094 | 0.83 | TDP1 (0.40) | TDP1STK17BSTK17AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339567-A1 | SUBSTITUTED IMIDAZOPYRIDINE AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | US | disclosed |
| US-20200308109-A1 | FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2020-10-01 | — | — | US | disclosed |
| EP-3700903-A1 | SUBSTITUTED IMIDAZOPYRIDINE AMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-09-02 | — | — | EP | disclosed |
| CN-111225917-A | Substituted imidazopyridine amides and uses thereof | 拜耳股份公司 | 2020-06-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308109-A1 | FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF | FH, PCK2, PC | TDP1 1371/4885STK17B 677/4885STK17A 525/4885 |
| US-20200339567-A1 | SUBSTITUTED IMIDAZOPYRIDINE AMIDES AND USE THEREOF | GOT2, ABAT, OAT | TDP1 1147/4885STK17B 2886/4885STK17A 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.