Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.31 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439618 | 1.00 | LPAR1 (0.41) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL29517377 | 1.00 | LPAR1 (0.41) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL29602431 | 0.91 | LPAR1 (0.41) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL28744725 | 0.91 | LPAR1 (0.47) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL24439733 | 0.90 | LPAR1 (0.41) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL29625494 | 0.90 | LPAR1 (0.41) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL24441058 | 0.88 | LPAR1 (0.38) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL29517762 | 0.87 | LPAR1 (0.43) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL24441034 | 0.87 | LPAR1 (0.43) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 | |
| SCHEMBL24439620 | 0.87 | LPAR1 (0.40) | LPAR1ABCC3ABCC4SLCO1B3SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |