Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026227 | 0.78 | GRM4 (0.38) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL31197987 | 0.78 | GRM4 (0.45) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL3956769 | 0.78 | GRM4 (0.45) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL3552924 | 0.73 | KDM4E (0.46) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL30475744 | 0.72 | GRM4 (0.38) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL29723811 | 0.71 | KDM4E (0.70) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL107964 | 0.71 | KDM4E (0.70) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL1852849 | 0.70 | PIM1 (0.47) | GRM4CTSAKDM4EALOX15TSHR | |
| SCHEMBL2632248 | 0.70 | ALDH1A1 (0.47) | GRM4CTSAKDM4EALOX15TSHR | |
| Hydrochloric Acid SCHEMBL11682457 | 0.70 | KDM4E (0.67) | GRM4CTSAKDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103899-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-19 | — | — | WO | disclosed |