SCHEMBL24440489

SCHEMBL24440489

C=C1C=CSC(c2ccc(CN)c(O)c2)=C1C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24440390 0.74 MAPT (0.32)
SCHEMBL24440482 0.67 CALML3 (0.31) CALML3
SCHEMBL10440353 0.63 TRPA1 (0.52)
SCHEMBL24440392 0.63 CALML3 (0.34) CALML3
SCHEMBL3924845 0.62 ALOX5 (0.57)
SCHEMBL15109932 0.62 VHL (0.44)
SCHEMBL26463095 0.62 PRMT5 (0.49)
Hydrochloric Acid SCHEMBL27095201 0.61 VHL (0.43) CALML3
SCHEMBL10414594 0.60 TYR (0.38)
SCHEMBL30255614 0.59 TYR (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022100710-A1 TYROSINE KINASE 2 (TYK2) DEGRADATION COMPOUNDS AND METHODS OF USE CULLGEN (SHANGHAI) , INC. (CN) 2022-05-19 WO disclosed