SCHEMBL24440656 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CSNK2A1	P68400	2/20	0.35

▸	KMO	O15229	4/20	0.34

▸	PDE4A	P27815	5/20	0.33

▸	PDE4B	Q07343	2/20	0.33

▸	PDE4C	Q08493	2/20	0.33

▸	PDE4D	Q08499	2/20	0.33

▸	MEN1	O00255	2/20	0.33

▸	KMT2A	Q03164	2/20	0.33

▸	NPY1R	P25929	1/20	0.33

▸	NPY2R	P49146	1/20	0.33

▸	HPGD	P15428	1/20	0.31

▸	MAPT	P10636	1/20	0.31

▸	SAE1	Q9UBE0	1/20	0.31

▸	LMNA	P02545	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24441148	0.90	CSNK2A1 (0.36)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL29672105	0.90	CSNK2A1 (0.36)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL29672295	0.89	KMO (0.36)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL24440640	0.89	CSNK2A1 (0.43)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL29601920	0.89	CSNK2A1 (0.43)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL24439734	0.89	KMO (0.36)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL24440655	0.89	MCHR1 (0.36)	—
SCHEMBL24439745	0.88	CSNK2A1 (0.34)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL24441480	0.87	CSNK2A1 (0.36)	CSNK2A1KMOPDE4APDE4BPDE4C
SCHEMBL28744808	0.85	LPAR1 (0.46)	KMOPDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022100623-A1	NITROGEN-SUBSTITUTED HETEROCYCLIC THIOPHENE COMPOUNDS AND USE THEREOF	武汉人福创新药物研发中心有限公司	2022-05-19	—	—	WO	disclosed