Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672295 | 1.00 | KMO (0.36) | KMOCSNK2A1SAE1RECQLPDE4D | |
| SCHEMBL29672105 | 0.90 | CSNK2A1 (0.36) | KMOCSNK2A1SAE1PDE4DPDE4B | |
| SCHEMBL24441148 | 0.90 | CSNK2A1 (0.36) | KMOCSNK2A1SAE1PDE4DPDE4B | |
| SCHEMBL29601920 | 0.89 | CSNK2A1 (0.43) | KMOCSNK2A1SAE1PDE4DPDE4B | |
| SCHEMBL24440656 | 0.89 | CSNK2A1 (0.35) | KMOCSNK2A1SAE1PDE4DPDE4B | |
| SCHEMBL24440640 | 0.89 | CSNK2A1 (0.43) | KMOCSNK2A1SAE1PDE4DPDE4B | |
| SCHEMBL24439694 | 0.89 | MCHR1 (0.36) | KMO | |
| SCHEMBL24439745 | 0.88 | CSNK2A1 (0.34) | KMOCSNK2A1SAE1PDE4DPDE4B | |
| SCHEMBL24441480 | 0.87 | CSNK2A1 (0.36) | KMOCSNK2A1SAE1RECQLPDE4D | |
| SCHEMBL24439731 | 0.87 | RIPK1 (0.33) | KMOCSNK2A1RECQLPDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100623-A1 | NITROGEN-SUBSTITUTED HETEROCYCLIC THIOPHENE COMPOUNDS AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |