Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 20/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24441137 | 1.00 | MALT1 (1.00) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL3727537 | 0.82 | MALT1 (0.76) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL3719743 | 0.76 | MALT1 (0.67) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL3719746 | 0.76 | MALT1 (0.67) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL2763440 | 0.76 | MALT1 (0.67) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL3119474 | 0.74 | MALT1 (0.88) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL612448 | 0.74 | MALT1 (0.64) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL14422627 | 0.68 | PIM1 (1.00) | MALT1 | |
| SCHEMBL14422651 | 0.66 | PIM1 (0.64) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL14422765 | 0.66 | PIM1 (0.67) | MALT1CYP3A4CYP2C9CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101676-A1 | MATERIALS AND METHODS OF TREATING CANCER | MONOPTEROS THERAPEUTICS,INC. (US) | 2022-05-19 | — | — | WO | disclosed |