Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.52 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | CSK | P41240 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 12/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197120 | 0.78 | SCN9A (0.50) | LCKSRCCSKBTKPARP10 | |
| SCHEMBL15756520 | 0.75 | CHEK1 (0.46) | BTK | |
| SCHEMBL202119 | 0.73 | PIK3CD (0.53) | PIK3CDNUDT14PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15074564 | 0.73 | MAPK1 (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL29709430 | 0.72 | LCK (0.45) | LCKBTKSCN9A | |
| SCHEMBL28849703 | 0.70 | KMT2A (0.46) | SMN1; SMN2RPS6KA3 | |
| SCHEMBL28034854 | 0.69 | SCN9A (0.52) | BTKEGFRPARP10SCN9ACHEK2 | |
| SCHEMBL25649413 | 0.69 | BTK (0.49) | BTKPARP10SCN9A | |
| SCHEMBL3135351 | 0.68 | PLAU (0.55) | BTKPARP10SCN9ACHEK2 | |
| SCHEMBL23239650 | 0.68 | BTK (0.60) | NUDT14NUDT5SRCBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018152-A1 | NOVEL PROCESS FOR THE PREPARATION OF (S)-7-(1-ACRYLOYLPIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE OR ITS SALTS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2024-01-18 | — | — | US | disclosed |
| US-20240018152-A1 | NOVEL PROCESS FOR THE PREPARATION OF (S)-7-(1-ACRYLOYLPIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE OR ITS SALTS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2024-01-18 | — | — | US | disclosed |
| US-20240018152-A1 | NOVEL PROCESS FOR THE PREPARATION OF (S)-7-(1-ACRYLOYLPIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE OR ITS SALTS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2024-01-18 | — | — | US | disclosed |
| WO-2022101939-A1 | NOVEL PROCESS FOR THE PREPARATION OF (S)-7-(1-ACRYLOYLPIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE OR ITS SALTS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2022-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018152-A1 | NOVEL PROCESS FOR THE PREPARATION OF (S)-7-(1-ACRYLOYLPIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE OR ITS SALTS THEREOF | CYP3A7, UGT1A7, UGT2B7 | PIK3CD 1582/4885NUDT14 775/4885PIK3CA 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.