Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.76 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.76 |
| ▸ | HTR2C | P28335 | 4/20 | 0.76 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809547 | 0.86 | HTR2A (1.00) | HTR2ATAAR1HTR2CHTR2B | |
| SCHEMBL29351348 | 0.86 | HTR2A (1.00) | HTR2ATAAR1HTR2CHTR2B | |
| SCHEMBL23478 | 0.86 | HTR2A (1.00) | HTR2ATAAR1HTR2CHTR2B | |
| SCHEMBL5351939 | 0.85 | TAAR1 (0.62) | HTR2ATAAR1HTR2CADRA1A | |
| Hydrochloric Acid SCHEMBL25285317 | 0.85 | HTR2A (0.96) | HTR2ATAAR1HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL22614747 | 0.85 | HTR2A (0.96) | HTR2ATAAR1HTR2CHTR2B | |
| Methane SCHEMBL20703126 | 0.85 | HTR2A (0.96) | HTR2ATAAR1HTR2CHTR2B | |
| SCHEMBL24959990 | 0.83 | HTR2A (0.68) | HTR2ATAAR1HTR2CHTR2BADRA1A | |
| SCHEMBL3469319 | 0.82 | HMGCR (0.60) | HTR2ATAAR1HTR2CSMN1; SMN2 | |
| SCHEMBL27795529 | 0.82 | HTR2A (0.52) | HTR2ATAAR1HTR2CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284736-B1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2021-03-03 | — | — | EP | disclosed |
| US-10155259-B2 | FSH receptor antagonists | MERCK SHARP & DOHME B.V. (NL) | 2018-12-18 | — | — | US | disclosed |
| EP-3284736-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUtech Ventures (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2763986-B1 | FSH RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (NL) | 2017-06-07 | — | — | EP | disclosed |
| EP-2763986-B1 | FSH RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (NL) | 2017-06-07 | — | — | EP | disclosed |
| EP-2537826-B1 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9302990-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150329545-A1 | FSH RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME B.V. (NL) | 2015-11-19 | — | — | US | disclosed |
| US-20150329545-A1 | FSH RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME B.V. (NL) | 2015-11-19 | — | — | US | disclosed |
| US-20150329545-A1 | FSH RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME B.V. (NL) | 2015-11-19 | — | — | US | disclosed |
| EP-0938676-A1 | COMBINATORIAL PROCESS FOR PREPARING THIAZOLIDINONE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5942387-A | Combinatorial process for preparing substituted thiophene libraries | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1999002990-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED SUBSTITUTED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998027087-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |
| WO-1998021584-A1 | COMBINATORIAL PROCESS FOR PREPARING THIAZOLIDINONE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| EP-0825164-A2 | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0818431-A1 | Scavenger assisted combinatorial process for preparing libaries of secondary amine compounds | ELI LILLY AND COMPANY (US) | 1998-01-14 | — | — | EP | disclosed |
| EP-0816309-A1 | Scavenger assisted combinatorial process for preparing libraries of urea and thiourea compounds | ELI LILLY AND COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10155259-B2 | FSH receptor antagonists | FSHR, GNRHR, LHCGR | HTR2A 1655/4885TAAR1 1131/4885HTR2C 2018/4885 |
| US-20150329545-A1 | FSH RECEPTOR ANTAGONISTS | FSHR, GNRHR, LHCGR | HTR2A 1655/4885TAAR1 1131/4885HTR2C 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.