Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 10/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | LONP1 | P36776 | 4/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.37 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.37 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.37 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.37 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24444088 | 1.00 | CCR1 (0.40) | CCR1PYGLCTSLCNR1CNR2 | |
| SCHEMBL20028504 | 0.90 | CCR1 (0.41) | CCR1PYGLCNR1CNR2 | |
| SCHEMBL22897279 | 0.90 | CCR1 (0.41) | CCR1PYGLCNR1CNR2 | |
| SCHEMBL20028172 | 0.85 | PYGL (0.41) | CCR1PYGLCNR1CNR2HDAC8 | |
| SCHEMBL20027519 | 0.85 | CAPN1 (0.53) | — | |
| SCHEMBL20027494 | 0.83 | HDAC8 (0.43) | CCR1PYGLCTSLCNR1CNR2 | |
| SCHEMBL20027817 | 0.83 | PYGL (0.41) | CCR1PYGLCTSLCNR1CNR2 | |
| SCHEMBL22896923 | 0.83 | PYGL (0.41) | CCR1PYGLCTSLCNR1CNR2 | |
| SCHEMBL20027892 | 0.80 | PYGL (0.44) | CCR1PYGLCNR1CNR2 | |
| SCHEMBL20028168 | 0.80 | PYGL (0.44) | CCR1PYGLCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | CCR1 4696/4885PYGL 925/4885CTSL 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.