Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.56 |
| ▸ | EGFR | P00533 | 9/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371619 | 0.92 | MET (0.66) | METKDRFLT3 | |
| SCHEMBL29693552 | 0.92 | MET (0.66) | METKDRFLT3 | |
| SCHEMBL12444048 | 0.83 | MET (0.54) | METKDR | |
| SCHEMBL15580178 | 0.81 | MET (0.53) | METKDRFLT3 | |
| SCHEMBL371713 | 0.81 | MET (0.69) | METKDRFLT3 | |
| SCHEMBL20525717 | 0.81 | MET (0.52) | METKDRFLT3 | |
| SCHEMBL20525810 | 0.80 | MET (0.68) | METKDRFLT3 | |
| SCHEMBL371726 | 0.80 | MET (0.64) | METKDR | |
| SCHEMBL372129 | 0.80 | MET (0.75) | METKDRFLT3 | |
| SCHEMBL20216672 | 0.80 | MET (0.54) | METEGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |