Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.66 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371619 | 1.00 | MET (0.66) | METKDRFLT3 | |
| SCHEMBL24444530 | 0.92 | MET (0.56) | METKDRFLT3 | |
| SCHEMBL12444048 | 0.90 | MET (0.54) | METKDR | |
| SCHEMBL371713 | 0.89 | MET (0.69) | METKDRFLT3 | |
| SCHEMBL15580178 | 0.89 | MET (0.53) | METKDRFLT3 | |
| SCHEMBL371726 | 0.89 | MET (0.64) | METKDR | |
| SCHEMBL372129 | 0.88 | MET (0.75) | METKDRFLT3 | |
| SCHEMBL20525717 | 0.88 | MET (0.52) | METKDRFLT3 | |
| SCHEMBL20525810 | 0.88 | MET (0.68) | METKDRFLT3 | |
| SCHEMBL371706 | 0.87 | MET (0.70) | METKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |