Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86956 | 0.78 | RAB9A (0.42) | CCR1RAB9ACCR5CYP1A2KDM4E | |
| SCHEMBL7213678 | 0.75 | KDM4E (0.34) | RAB9AKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8268446 | 0.75 | CCR1 (0.39) | CCR1RAB9ACCR5CYP1A2KDM4E | |
| SCHEMBL8353367 | 0.75 | RAB9A (0.39) | CCR1RAB9ACCR5CYP1A2KDM4E | |
| SCHEMBL31204615 | 0.75 | KDM4E (0.42) | CCR1RAB9ACCR5CYP1A2KDM4E | |
| SCHEMBL8563062 | 0.69 | ALDH1A1 (0.56) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19067625 | 0.68 | KDM4E (0.42) | CCR1RAB9ACCR5CYP1A2KDM4E | |
| SCHEMBL20722611 | 0.68 | IKBKB (0.50) | RAB9AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL29707424 | 0.68 | IKBKB (0.50) | RAB9AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL8800681 | 0.67 | IKBKB (0.39) | CCR1RAB9ACCR5CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001277-A2 | BICYCLIC COMPOUNDS FOR DIAGNOSIS AND THERAPY | AC Immune SA (CH) | 2022-05-25 | — | — | EP | disclosed |