SCHEMBL24445337

SCHEMBL24445337

C1=CC2Oc3cc(-c4ccc(-c5nc(-c6ccccc6)nc(-c6ccc(-c7ccccc7)cc6)n5)cc4)ccc3C2C=C1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.36
ADORA1 P30542 4/20 0.36
MEN1 O00255 7/20 0.36
KMT2A Q03164 7/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 3/20 0.35
LMNA P02545 2/20 0.35
GLA P06280 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
PKM P14618 1/20 0.35
ADORA3 P0DMS8 2/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
DPP4 P27487 1/20 0.33
NTSR1 P30989 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25944795 0.91 ADORA2A (0.33) ADORA2AADORA1MEN1KMT2AMAPT
SCHEMBL21662105 0.91 L3MBTL1 (0.45) ADORA2AADORA1MEN1KMT2AMAPT
SCHEMBL25945945 0.90 MEN1 (0.31) ADORA2AADORA1MEN1KMT2AMAPT
SCHEMBL23944836 0.88 ADORA2A (0.32) ADORA2AADORA1MEN1KMT2AMAPT
SCHEMBL27340875 0.85 EDNRB (0.33) KDM4ELMNAL3MBTL1USP2CYP1A2
SCHEMBL25442351 0.84 KDM4E (0.33) MEN1KMT2AKDM4EGAA
SCHEMBL26327992 0.83
SCHEMBL23823718 0.82 PIM1 (0.33)
SCHEMBL23934782 0.81 TAAR1 (0.35) ALDH1A1CYP3A4HSD17B10
SCHEMBL26589294 0.81 ADORA2A (0.34) ADORA2AADORA1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4002509-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2022-05-25 EP disclosed