SCHEMBL25945945

SCHEMBL25945945

Clc1nc(-c2cccc(-c3ccccc3)c2)nc(-c2ccc3c(c2)OC2C=CC=CC32)n1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
GP6 Q9HCN6 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25944795 0.96 ADORA2A (0.33) MEN1ALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL24445337 0.90 ADORA2A (0.36) MEN1ALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL23253855 0.89
SCHEMBL21662105 0.85 L3MBTL1 (0.45) MEN1ALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL23944836 0.82 ADORA2A (0.32) MEN1ALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL27340875 0.79 EDNRB (0.33) L3MBTL1KDM4E
SCHEMBL23823718 0.78 PIM1 (0.33)
SCHEMBL25442351 0.78 KDM4E (0.33) MEN1KMT2AKDM4E
SCHEMBL26327992 0.77
SCHEMBL21861098 0.77 MEN1 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219484-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-08-02 EP disclosed