Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615308 | 0.75 | RECQL (0.41) | RAB9AKMT2AMEN1NPC1HTT | |
| SCHEMBL19897765 | 0.75 | RECQL (0.41) | RAB9AKMT2AMEN1NPC1HTT | |
| SCHEMBL10163642 | 0.73 | CYP4F2 (0.40) | RAB9AKMT2AMEN1NPC1HTT | |
| SCHEMBL29348329 | 0.69 | HTT (0.35) | RAB9AKMT2AMEN1NPC1HTT | |
| SCHEMBL7105655 | 0.68 | DDB1 (0.53) | RAB9AKMT2AMEN1NPC1HTT | |
| SCHEMBL19939439 | 0.68 | HTR7 (0.43) | RAB9AKMT2ANPC1HDAC8HDAC3 | |
| SCHEMBL31042792 | 0.66 | GAA (0.46) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL25138047 | 0.66 | GAA (0.46) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL19939559 | 0.66 | DPP7 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL22848292 | 0.66 | KAT2B (0.40) | RAB9AKMT2AMEN1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507284-B1 | BIARYL COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2022-05-25 | — | — | EP | disclosed |