Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897765 | 1.00 | RECQL (0.41) | RECQLMAPTPRKD3PRKCGPRKCB | |
| SCHEMBL19897911 | 0.83 | ATM (0.55) | RECQLMAPTATMALDH1A1FABP4 | |
| SCHEMBL7673435 | 0.77 | CA12 (0.64) | MAPTALDH1A1SMN1; SMN2KMT2ACA12 | |
| SCHEMBL16509830 | 0.77 | ALPL (0.47) | MAPTATMALDH1A1KMT2AMEN1 | |
| SCHEMBL19450347 | 0.76 | SIGMAR1 (0.50) | ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL19897885 | 0.76 | RECQL (0.49) | RECQLMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL24445447 | 0.75 | RAB9A (0.36) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL8576412 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL10163642 | 0.73 | CYP4F2 (0.40) | ALDH1A1KMT2AHTTMEN1NPC1 | |
| SCHEMBL7650172 | 0.72 | PRMT1 (0.52) | ATMALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507284-B1 | BIARYL COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2022-05-25 | — | — | EP | disclosed |