Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19579749 | 0.79 | RXRA (0.40) | HPGDKMT2ALMNATSHRCA12 | |
| SCHEMBL507936 | 0.70 | KMT2A (0.64) | SRD5A2SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL11733309 | 0.68 | CA12 (0.53) | SMN1; SMN2HPGDNPSR1KMT2ALMNA | |
| SCHEMBL14677744 | 0.67 | LMNA (0.52) | SRD5A2SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8884700 | 0.64 | KDM4E (0.50) | SMN1; SMN2NPC1RAB9AHPGDNPSR1 | |
| SCHEMBL9005582 | 0.64 | PDE4A (0.59) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL6920980 | 0.62 | LMNA (0.54) | SMN1; SMN2NPC1RAB9AHPGDNPSR1 | |
| SCHEMBL28803763 | 0.62 | LMNA (0.65) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL26685419 | 0.62 | KMT2A (0.55) | PTGDR2KMT2ALMNACA12CA1 | |
| SCHEMBL1458531 | 0.62 | KMT2A (0.50) | RAB9AKMT2ATSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4000610-A1 | PHARMACOLOGY OF VISUAL CYCLE MODULATORS | Acucela Inc. (US) | 2022-05-25 | — | — | EP | disclosed |