SCHEMBL24445720

SCHEMBL24445720

CCCCc1ccc(Nc2ccc(CC)cc2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
MAPK1 P28482 2/20 0.45
HTT P42858 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TRPA1 O75762 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 2/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
ALOX12 P18054 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24445719 0.87 MAPK1 (0.50) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL19985672 0.83 HPGD (0.44) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL16542333 0.78 HPGD (0.43) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL24037355 0.78 PPARA (0.58) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL48879 0.76 HPGD (0.58) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL14127779 0.76 HPGD (0.58) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL9129626 0.75 NPC1 (0.61) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL14127780 0.75 HPGD (0.49) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL2542906 0.75 HPGD (0.46) HPGDNPC1RAB9AMAPK1HTT
SCHEMBL1422741 0.75 HPGD (0.54) HPGDNPC1RAB9AMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3516019-B1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS CORP (US) 2023-06-14 EP disclosed
EP-3516020-B1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS LANXESS CORP (US) 2022-05-25 EP disclosed