SCHEMBL19985672

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24445720	0.83	HPGD (0.45)	HPGDNPC1RAB9AALDH1A1CA12
	SCHEMBL24445719	0.82	MAPK1 (0.50)	HPGDNPC1RAB9AALDH1A1CA12
	SCHEMBL7652240	0.81	HPGD (0.50)	HPGDNPC1RAB9ANR1H4ALDH1A1
	SCHEMBL9701622	0.80	UNG (0.44)	ALDH1A1LMNAHSD17B10PLK1STS
	SCHEMBL19987340	0.78	ALDH1A1 (0.48)	HPGDNPC1RAB9AALDH1A1MAPT
	SCHEMBL19985758	0.75	HPGD (0.46)	HPGDNPC1RAB9ANR1H4ALDH1A1
	SCHEMBL547838	0.74	KCNH2 (0.60)	HPGDNPC1RAB9AALDH1A1CA1
	SCHEMBL9711161	0.73	ESR1 (0.63)	ALDH1A1CA1CA2MEN1LMNA
	SCHEMBL19985670	0.72	ALDH1A1 (0.48)	HPGDALDH1A1MAPTMEN1GAA
	SCHEMBL48879	0.72	HPGD (0.58)	HPGDNPC1RAB9AALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.