Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445710 | 0.86 | — | — | |
| SCHEMBL7996760 | 0.65 | — | — | |
| SCHEMBL17713603 | 0.61 | KDM4E (0.31) | KDM4E | |
| SCHEMBL7830998 | 0.61 | — | — | |
| SCHEMBL11418036 | 0.60 | CES2 (0.38) | KDM4EMEN1CES2ALDH1A1TP53 | |
| SCHEMBL21443828 | 0.60 | S100A4 (0.43) | KDM4EMEN1CES2ALDH1A1TP53 | |
| SCHEMBL12500062 | 0.55 | MEN1 (0.39) | KDM4EMEN1CES2ALDH1A1TP53 | |
| SCHEMBL1387747 | 0.55 | CES2 (0.44) | KDM4EMEN1CES2ALDH1A1TP53 | |
| SCHEMBL9615320 | 0.53 | MAP3K14 (0.35) | KDM4EMEN1CES2ALDH1A1TP53 | |
| SCHEMBL164583 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001288-A1 | PROCESS FOR THE PREPARATION OF TRENBOLONE ACETATE HAVING A DEFINITE PARTICLE SIZE DISTRIBUTION AND A IRREGULAR HEXAGON PLATES CRYSTAL HABIT | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2022-05-25 | — | — | EP | disclosed |