SCHEMBL2444810

SCHEMBL2444810

CCn1c2ccc(C(=O)c3cccc(C)c3)cc2c2cc(/C(C)=N/OC(C)=O)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
HPGD P15428 4/20 0.50
HTT P42858 2/20 0.50
MAPT P10636 5/20 0.48
LMNA P02545 5/20 0.48
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CNR2 P34972 1/20 0.42
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350878 1.00 KDM4E (0.50) KDM4EHPGDHTTMAPTLMNA
SCHEMBL2391309 1.00 KDM4E (0.50) KDM4EHPGDHTTMAPTLMNA
SCHEMBL103772 0.90 KDM4E (0.54) KDM4EHPGDHTTMAPTLMNA
SCHEMBL2392386 0.90 KDM4E (0.54) KDM4EHPGDHTTMAPTLMNA
SCHEMBL29367206 0.90 KDM4E (0.54) KDM4EHPGDHTTMAPTLMNA
SCHEMBL2735113 0.90 KDM4E (0.58) KDM4EHPGDHTTMAPTLMNA
SCHEMBL4752867 0.90 KDM4E (0.58) KDM4EHPGDHTTMAPTLMNA
SCHEMBL28541974 0.87 KDM4E (0.51) KDM4EHPGDHTTMAPTLMNA
SCHEMBL14066500 0.86 KDM4E (0.49) KDM4EHPGDHTTMAPTLMNA
SCHEMBL19621069 0.86 KDM4E (0.49) KDM4EHPGDHTTMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111989317-B Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, and polarizing plate 日本瑞翁株式会社 2023-12-01 CN disclosed
CN-110382471-B Polymerizable compound, polymerizable liquid crystal mixture, polymer, optical film, optically anisotropic body, polarizing plate, display device, antireflection film, and compound 日本瑞翁株式会社 2023-09-01 CN disclosed
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 EP disclosed
US-11492552-B2 Polymerizable liquid crystal material, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, polarizing plate, anti-reflection film, display device, and method of producing polymerizable liquid crystal composition ZEON CORPORATION (JP) 2022-11-08 US disclosed
CN-111095050-B Polymerizable liquid crystal material, composition, polymer, film, anisotropic body, polarizing plate, device, and method for producing composition 日本瑞翁株式会社 2022-06-07 CN disclosed
CN-109952323-B Polymerizable compound, mixture, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, polarizing plate, display device, and antireflection film 日本瑞翁株式会社 2022-01-21 CN disclosed
CN-109890858-B Mixture, polymerizable composition, polymer, optical film, optically anisotropic body, and method for using polymerizable compound 日本瑞翁株式会社 2021-12-24 CN disclosed
US-11203716-B2 Compound, polymerizable compound, mixture, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic product, polarizing plate, flat panel display device, organic electroluminescence display device, and anti-reflection film ZEON CORPORATION (JP) 2021-12-21 US disclosed
CN-110003008-B Mixtures and compounds 日本瑞翁株式会社 2021-11-09 CN disclosed
US-20140107247-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY ZEON CORPORATION (JP) 2014-04-17 US disclosed
EP-2703385-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2014-03-05 EP disclosed
EP-2698388-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY Zeon Corporation (JP) 2014-02-19 EP disclosed
US-8268201-B2 Color composition for color filter, color filter using the composition and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2012-09-18 US disclosed
US-8262946-B2 Color composition for color filter, color filter using the composition and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2012-09-11 US disclosed
CN-102221777-A White photosensitive resin composition and white matrix, color filter and reflective display assembly thereof CHI MEI IND CO LTD 2011-10-19 CN disclosed
US-20110215284-A1 Color composition for color filter, color filter using the composition and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2011-09-08 US disclosed
US-20100295002-A1 Color composition for color filter, color filter using the composition and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2010-11-25 US disclosed
EP-2012182-A2 Radiation-sensitive composition for forming color filter for solid-state image sensing device, color filter, and solid-state image sensing device JSR Corporation (JP) 2009-01-07 EP disclosed
US-20090004578-A1 RADIATION-SENSITIVE COMPOSITION FOR FORMING COLOR FILTER FOR SOLID-STATE IMAGE SENSING DEVICE, COLOR FILTER, AND SOLID-STATE IMAGE SENSING DEVICE JSR CORPORATION (JP) 2009-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11203716-B2 Compound, polymerizable compound, mixture, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic product, polarizing plate, flat panel display device, organic electroluminescence display device, and anti-reflection film NR2E3, NR3C2, NR2C2 KDM4E 3775/4885HPGD 4256/4885HTT 2177/4885
US-20140107247-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY H1-0, H1-2, H1-4 KDM4E 1909/4885HPGD 4782/4885HTT 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.