SCHEMBL2735113

SCHEMBL2735113

CCn1c2ccc(C(=O)c3ccc(C(=O)c4ccc5c(c4)c4cc(/C(C)=N/OC(C)=O)ccc4n5CC)cc3)cc2c2cc(/C(C)=N/OC(C)=O)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.58
HPGD P15428 5/20 0.58
HTT P42858 2/20 0.58
LMNA P02545 3/20 0.52
MAPT P10636 3/20 0.52
TUBB4A P04350 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48
TUBA4A P68366 1/20 0.48
TUBB4B P68371 1/20 0.48
TUBB3 Q13509 1/20 0.48
TUBB2A Q13885 1/20 0.48
TUBB8 Q3ZCM7 1/20 0.48
TUBA3E Q6PEY2 1/20 0.48
TUBA1A Q71U36 1/20 0.48
TUBA1C Q9BQE3 1/20 0.48
TUBB6 Q9BUF5 1/20 0.48
TUBB2B Q9BVA1 1/20 0.48
TUBB1 Q9H4B7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4752867 1.00 KDM4E (0.58) KDM4EHPGDHTTLMNAMAPT
SCHEMBL2392386 0.95 KDM4E (0.54) KDM4EHPGDHTTLMNAMAPT
SCHEMBL103772 0.95 KDM4E (0.54) KDM4EHPGDHTTLMNAMAPT
SCHEMBL29367206 0.95 KDM4E (0.54) KDM4EHPGDHTTLMNAMAPT
SCHEMBL20022370 0.93 TUBB4A (0.53) KDM4EHPGDHTTLMNAMAPT
SCHEMBL28541974 0.92 KDM4E (0.51) KDM4EHPGDHTTLMNAMAPT
SCHEMBL18353953 0.90 KDM4E (0.51) KDM4EHPGDHTTLMNAMAPT
SCHEMBL29350878 0.90 KDM4E (0.50) KDM4EHPGDHTTLMNAMAPT
SCHEMBL22824357 0.90 KDM4E (0.51) KDM4EHPGDHTTLMNAMAPT
SCHEMBL2444810 0.90 KDM4E (0.50) KDM4EHPGDHTTLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088836-B2 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. (JP) 2012-01-03 US disclosed
US-8088836-B2 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. (JP) 2012-01-03 US disclosed
US-20100210749-A1 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. 2010-08-19 US disclosed
US-20100210749-A1 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. 2010-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210749-A1 Oxime ester compounds and photosensitive resin compositions using the same PPOX, FTO, NR2E3 KDM4E 42/4885HPGD 560/4885HTT 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.