Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514968 | 1.00 | TAS2R38 (0.39) | TAS2R38HSD17B10GAANPC1RAB9A | |
| SCHEMBL18473251 | 0.84 | GAA (0.45) | TAS2R38HSD17B10GAANPC1RAB9A | |
| SCHEMBL20008068 | 0.84 | TGM2 (0.47) | TAS2R38HSD17B10GAANPC1RAB9A | |
| SCHEMBL12344947 | 0.84 | TGM2 (0.43) | TAS2R38HSD17B10GAANPC1RAB9A | |
| SCHEMBL24158448 | 0.84 | TAS2R38 (0.42) | TAS2R38HSD17B10GAANPC1RAB9A | |
| SCHEMBL15292671 | 0.84 | TGM2 (0.47) | TAS2R38HSD17B10GAANPC1RAB9A | |
| SCHEMBL19176338 | 0.79 | MAOB (0.42) | TAS2R38HSD17B10GAANPC1RAB9A | |
| SCHEMBL18949936 | 0.78 | MAPT (0.45) | HSD17B10GAARAB9AKMT2AMEN1 | |
| SCHEMBL25805470 | 0.78 | MAPT (0.32) | ALDH1A1MAPT | |
| SCHEMBL13626039 | 0.78 | MAPT (0.45) | HSD17B10GAARAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220165954-A1 | FORMULATION CONTAINING A CROSSLINKABLE POLYMER | MERCK PATENT GMBH (DE) | 2022-05-26 | — | — | US | disclosed |