Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | DBH | P09172 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 8/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24451072 | 0.86 | CES2 (0.47) | MEN1KMT2ACES2KDM4EDBH | |
| SCHEMBL11347585 | 0.84 | HSP90AA1 (0.55) | MEN1KMT2AKDM4EDBHGAA | |
| SCHEMBL12780275 | 0.83 | PDE2A (0.47) | MEN1KMT2ACES2KDM4EGAA | |
| SCHEMBL29033140 | 0.81 | KDM4E (0.60) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30450981 | 0.81 | KDM4E (0.56) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26732909 | 0.81 | KDM4E (0.56) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL320481 | 0.80 | CES2 (0.52) | MEN1KMT2ACES2KDM4ETMPRSS4 | |
| SCHEMBL30062195 | 0.80 | CES2 (0.52) | MEN1KMT2ACES2KDM4ETMPRSS4 | |
| SCHEMBL1033788 | 0.79 | GAA (0.54) | CES2KDM4EGAAALDH1A1HPGD | |
| SCHEMBL13688467 | 0.79 | CES2 (0.66) | CES2KDM4EGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162209-A1 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162209-A1 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | ADSL, SLC35B2, ADORA1 | MEN1 3736/4885KMT2A 4242/4885CES2 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.