Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152183 | 0.82 | GAA (0.72) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL2234017 | 0.82 | GAA (0.72) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL7690167 | 0.82 | KDM4E (0.46) | GAAJAK2LMNAMAPTCA1 | |
| SCHEMBL11322586 | 0.81 | GAA (0.70) | GAAJAK2LMNAMAPTTSHR | |
| Methane SCHEMBL7356487 | 0.80 | GAA (0.69) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL10786863 | 0.80 | GAA (0.70) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL2637278 | 0.80 | GAA (0.95) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL9150153 | 0.79 | GAA (0.67) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL4537436 | 0.78 | GAA (0.67) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL9045649 | 0.78 | GAA (0.82) | GAAJAK2LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735847-B | Synthetic preparation method of berberine hydrochloride | 四川大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113735847-A | Synthetic preparation method of berberine hydrochloride | 四川大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-108993485-B | Preparation method and application of in-situ supported metal mesoporous carbon microsphere catalyst | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-107739075-B | Electrocatalytic reduction dechlorination method for wastewater containing chlorinated organic pollutants | 广西大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-108993485-A | The preparation method and application of a kind of mesoporous carbon microspherical catalyst of original position carried metal | 浙江工业大学 | 2018-12-14 | — | — | CN | disclosed |
| EP-1483378-B1 | RECYCLING SYSTEM FOR MANIPULATION OF INTRACELLULAR NADH AVAILABILITY | RICE UNIVERSITY (US) | 2013-01-02 | — | — | EP | disclosed |
| US-8017374-B2 | Using marine fungus to remove colored effluents from textile mill, dye-making, paper and pulp and molasses spent washes from alcohol distilleries; bioremediation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2011-09-13 | — | — | US | disclosed |
| US-20100184195-A1 | Recycling System for Manipulation of Intracellular NADH Availability | RICE UNIVERSITY (US) | 2010-07-22 | — | — | US | disclosed |
| US-7709261-B2 | Recycling system for manipulation of intracellular NADH availability | RICE UNIVERSITY (US) | 2010-05-04 | — | — | US | disclosed |
| EP-2035425-A1 | AMINO- IMIDAZOLONES AND THEIR USE AS A MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT, ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA. | AstraZeneca AB (SE) | 2009-03-18 | — | — | EP | disclosed |
| US-6133483-A | Process for the production of 2,4,4'-trichloro-2'-methoxydiphenyl ether | CLEARY THOMAS F (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1009738-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AS PROTEIN TYROSINE KINASE AND AS PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-06-21 | — | — | EP | disclosed |
| EP-0973501-A2 | AQUEOUS SUSPENSION FOR NASAL ADMINISTRATION OF LOTEPREDNOL | Senju Pharmaceutical Co., Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999015500-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AS PROTEIN TYROSINE KINASE AND AS PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1999-04-01 | — | — | WO | disclosed |
| WO-1998031343-A2 | AQUEOUS SUSPENSION FOR NASAL ADMINISTRATION OF LOTEPREDNOL | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-23 | — | — | WO | disclosed |
| US-5378367-A | Hydrotalcite, activated carbon | ALUMINUM COMPANY OF AMERICA (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1988009842-A1 | A METHOD OF REDUCING CHLOROPHENOL COMPOUNDS IN THE CHLORINE BLEACHING OF PULP | CARNOE NILS BERTIL (SE) | 1988-12-15 | — | — | WO | disclosed |
| EP-0144416-A1 | METHOD FOR REDUCING THE HYDROCARBON CONTENT IN AIR OR WATER | MUNTERS ZEOL AB (SE) | 1985-06-19 | — | — | EP | disclosed |
| WO-1984004913-A1 | METHOD FOR REDUCING THE HYDROCARBON CONTENT IN AIR OR WATER | ZEOL AB (SE) | 1984-12-20 | — | — | WO | disclosed |
| US-4001284-A | PRIMARY AMINES, 2,4-DIPHENOXY-5-SULFAMOYLBENZOIC ACID | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |