SCHEMBL9045649

SCHEMBL9045649

Oc1ccccc1OCCCCOc1ccccc1O

nearest known ligand 0.82

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.82
JAK2 O60674 1/20 0.82
LMNA P02545 1/20 0.82
MAPT P10636 1/20 0.82
DRD2 P14416 1/20 0.56
DRD4 P21917 1/20 0.56
DRD3 P35462 1/20 0.56
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
APP P05067 1/20 0.52
NPC1 O15118 1/20 0.48
POLB P06746 1/20 0.48
PTK2B Q14289 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24011910 0.98 GAA (0.78) GAAJAK2LMNAMAPTDRD2
SCHEMBL9123832 0.98 GAA (0.78) GAAJAK2LMNAMAPTDRD2
SCHEMBL5621969 0.95 GAA (0.82) GAAJAK2LMNAMAPTDRD2
SCHEMBL2637278 0.92 GAA (0.95) GAAJAK2LMNAMAPTDRD2
SCHEMBL9150153 0.89 GAA (0.67) GAAJAK2LMNAMAPTDRD2
SCHEMBL462067 0.89 LMNA (0.67) GAAJAK2LMNAMAPTDRD2
SCHEMBL11601635 0.89 GAA (0.67) GAAJAK2LMNAMAPTDRD2
SCHEMBL8765738 0.89 GAA (0.67) GAAJAK2LMNAMAPTDRD2
SCHEMBL9152183 0.89 GAA (0.72) GAAJAK2LMNAMAPTDRD2
SCHEMBL29434581 0.89 GAA (0.72) GAAJAK2LMNAMAPTDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8134005-A None JP disclosed
JP-H08134005-A 1,4-BIS(2-HYDROXYPHENOXY)BUTANE, ITS ALKALI METAL SALT AND THEIR PRODUCTION NIPPON GREEN CONSULTANT KK 1996-05-28 JP disclosed
US-5386008-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1995-01-31 US disclosed
US-5244998-A Flexible coatings THE DOW CHEMICAL COMPANY (US) 1993-09-14 US disclosed
US-5147905-A Cationic polyepoxide and epoxy resins for electrodeposition; flexibility; workability THE DOW CHEMICAL COMPANY (US) 1992-09-15 US disclosed
EP-0483352-A1 ADVANCED AND UNADVANCED EPOXY RESIN COMPOSITIONS, NUCLEOPHILIC DERIVATIVES THEREOF AND CURABLE AND COATING COMPOSITIONS THEREOF THE DOW CHEMICAL COMPANY (US) 1992-05-06 EP disclosed
WO-1991018034-A1 ADVANCED AND UNADVANCED COMPOSITIONS, NUCLEOPHILIC DERIVATIVES THEREOF AND CURABLE AND COATING COMPOSITIONS THEREOF THE DOW CHEMICAL COMPANY (US) 1991-11-28 WO disclosed