Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 9/20 | 0.40 |
| ▸ | IDH2 | P48735 | 3/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937066 | 0.84 | ADORA3 (0.43) | ADORA3ADORA1IDH1IDH2KMT2A | |
| SCHEMBL27225176 | 0.82 | ADORA3 (0.41) | ADORA3ADORA1IDH1IDH2KMT2A | |
| SCHEMBL1496403 | 0.80 | TDP1 (0.39) | ADORA3ADORA1KMT2AAXL | |
| SCHEMBL21299386 | 0.74 | ADORA3 (0.40) | ADORA3ADORA1IDH1IDH2LDHA | |
| SCHEMBL15794930 | 0.74 | JAK2 (0.42) | — | |
| SCHEMBL15174990 | 0.73 | CSF1R (0.40) | ADORA3ADORA1IDH1IDH2KMT2A | |
| SCHEMBL16377048 | 0.73 | CSF1R (0.40) | ADORA3ADORA1IDH1IDH2KMT2A | |
| SCHEMBL15174989 | 0.73 | CSF1R (0.40) | ADORA3ADORA1IDH1IDH2KMT2A | |
| SCHEMBL4194114 | 0.73 | CRHR1 (0.43) | ADORA3ADORA1KMT2A | |
| SCHEMBL15749135 | 0.73 | IDH1 (0.40) | ADORA3ADORA1IDH1IDH2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022106547-A1 | PROCESS FOR SYNTHESISING A ROR GAMMA INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-27 | — | — | WO | disclosed |