Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24456998 | 1.00 | DPP4 (0.41) | DPP4DPP8DPP7DPP9MEN1 | |
| SCHEMBL24456648 | 1.00 | DPP4 (0.41) | DPP4DPP8DPP7DPP9MEN1 | |
| SCHEMBL24844030 | 0.89 | ALDH1A1 (0.44) | DPP4MEN1KMT2APOLBMAPT | |
| SCHEMBL2603234 | 0.89 | ALDH1A1 (0.41) | DPP4DPP8DPP7DPP9MEN1 | |
| SCHEMBL19229731 | 0.87 | CHRNB2 (0.44) | DPP4DPP8DPP7DPP9MEN1 | |
| SCHEMBL24972572 | 0.87 | CHRNB2 (0.44) | DPP4DPP8DPP7DPP9MEN1 | |
| SCHEMBL24448937 | 0.86 | DPP4 (0.45) | DPP4DPP8DPP7DPP9MEN1 | |
| SCHEMBL24457531 | 0.84 | ALDH1A1 (0.42) | DPP4MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL24456611 | 0.84 | ALDH1A1 (0.42) | DPP4MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL19735100 | 0.84 | CHRNB2 (0.35) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022106857-A1 | MALT-1 MODULATORS | Exscientia Limited (GB) | 2022-05-27 | — | — | WO | disclosed |