Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | KIF5B | P33176 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 16/20 | 0.44 |
| ▸ | ABL1 | P00519 | 15/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.44 |
| ▸ | EGFR | P00533 | 13/20 | 0.44 |
| ▸ | HCK | P08631 | 13/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.44 |
| ▸ | MTOR | P42345 | 13/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 13/20 | 0.44 |
| ▸ | PRKDC | P78527 | 13/20 | 0.44 |
| ▸ | KDR | P35968 | 12/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458853 | 0.88 | RET (0.47) | RETKIF5BDYRK1ASRCABL1 | |
| SCHEMBL29407669 | 0.82 | SRC (0.52) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL22658699 | 0.82 | SRC (0.52) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL24458348 | 0.78 | RET (0.56) | RETKIF5BDYRK1ASRCABL1 | |
| SCHEMBL130481 | 0.78 | PIK3CD (0.71) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31264762 | 0.78 | CYP3A4 (0.51) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL29552386 | 0.77 | RET (0.44) | RETKIF5BDYRK1ASRCABL1 | |
| SCHEMBL30582543 | 0.76 | KDM4E (0.49) | RETDYRK1ASRCKDRTEK | |
| SCHEMBL26105843 | 0.76 | KDM4E (0.49) | RETDYRK1ASRCKDRTEK | |
| SCHEMBL29552528 | 0.76 | RET (0.43) | RETKIF5BDYRK1ASRCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154154-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. | 2025-05-15 | — | — | US | disclosed |
| EP-4247816-A1 | SRC INHIBITORS AND USES THEREOF | Relay Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154154-A1 | SRC INHIBITORS AND USES THEREOF | SRC, LCK, FYN | RET 56/4885KIF5B 1634/4885DYRK1A 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.