Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18543262 | 0.81 | MPO (0.44) | MPOFFAR4KCNH2SLC6A4SLC6A2 | |
| SCHEMBL16958568 | 0.81 | FFAR4 (0.43) | MPOFFAR4KCNH2SLC6A4SLC6A2 | |
| SCHEMBL15073262 | 0.81 | FFAR4 (0.43) | MPOFFAR4KCNH2SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL23753825 | 0.80 | MPO (0.43) | MPOFFAR4KCNH2SLC6A4SLC6A2 | |
| SCHEMBL24459310 | 0.80 | FFAR4 (0.41) | FFAR4KCNH2SLC6A4IDO1HTR2A | |
| SCHEMBL24459266 | 0.79 | GRIN2B (0.43) | KCNH2SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL17449715 | 0.77 | KCNH2 (0.41) | MPOFFAR4KCNH2SLC6A4SLC6A2 | |
| SCHEMBL18588991 | 0.77 | SLC6A4 (0.59) | MPOKCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27856227 | 0.74 | EPHX2 (0.39) | MPOFFAR4KCNH2SLC6A4SLC6A2 | |
| SCHEMBL30568364 | 0.74 | GPR3 (0.46) | GPR3EPHX2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109078-A1 | AROMATIC BORON-CONTAINING COMPOUNDS AND INSULIN ANALOGS | PROTOMER TECHNOLOGIES INC. (US) | 2022-05-27 | — | — | WO | disclosed |