SCHEMBL2446004

SCHEMBL2446004

CCn1c(=O)n(CC)c(=O)n(CC)c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 5/20 0.48
GSK3A P49840 4/20 0.48
F2 P00734 1/20 0.44
ELANE P08246 1/20 0.44
CTSG P08311 1/20 0.44
CTRC Q99895 1/20 0.44
ALDH1A1 P00352 5/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
GFER P55789 1/20 0.43
ADORA2A P29274 2/20 0.40
ADORA2B P29275 1/20 0.40
CYP1A2 P05177 1/20 0.39
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
THPO P40225 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26452124 0.85 GSK3B (0.39) GSK3BGSK3AF2ELANECTSG
SCHEMBL21974369 0.85 GSK3A (0.50) GSK3BGSK3AADORA2AADORA2BCYP1A2
SCHEMBL23020227 0.85 GSK3A (0.50) GSK3BGSK3AADORA2AADORA2BCYP1A2
SCHEMBL8456337 0.81 GSK3B (0.41) GSK3BGSK3AF2ELANECTSG
SCHEMBL13839599 0.81 ALDH1A1 (0.47) GSK3BGSK3AF2ELANECTSG
SCHEMBL29195195 0.81 GSK3B (0.41) GSK3BGSK3AALDH1A1MAPTKDM4E
SCHEMBL838751 0.81 GSK3B (0.41) GSK3BGSK3AALDH1A1MAPTKDM4E
SCHEMBL16811759 0.81 GSK3B (0.41) GSK3BGSK3AF2ELANECTSG
SCHEMBL20392162 0.81 RGS4 (0.53) GSK3BGSK3AALDH1A1ADORA2AADORA2B
SCHEMBL24305242 0.79 GSK3A (0.35) GSK3BGSK3AF2ELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085215-A Low-odor flame-retardant acrylic polyurethane resin and preparation method and application thereof 上海华谊精细化工有限公司 2024-05-28 CN claimed
CN-117757045-A Polyester resin for boron nitride and polyaniline modified powder coating and preparation method thereof 浙江传化天松新材料有限公司 2024-03-26 CN claimed
CN-116042007-B Flame-retardant insulating coating for power battery and preparation method thereof 上海汇得科技股份有限公司 2024-03-19 CN claimed
CN-117285842-B Modified color paste, bi-component aromatic polyurethane material and preparation method thereof 黎明化工研究设计院有限责任公司 2024-02-27 CN claimed
CN-117285842-A Modified color paste, bi-component aromatic polyurethane material and preparation method thereof 黎明化工研究设计院有限责任公司 2023-12-26 CN claimed
CN-116042007-A Flame-retardant insulating coating for power battery and preparation method thereof 上海汇得科技股份有限公司 2023-05-02 CN claimed
CN-112670577-B Electrolyte, preparation method thereof and lithium ion battery 惠州亿纬锂能股份有限公司 2022-07-12 CN claimed
CN-112670577-A Electrolyte, preparation method thereof and lithium ion battery 惠州亿纬锂能股份有限公司 2021-04-16 CN claimed
CN-112552854-A Conductive adhesive and preparation method thereof 山东万圣博化工有限公司 2021-03-26 CN claimed
US-7419622-B2 Stabilizer composition for halogen-containing thermoplastic resin compositions BARLOCHER GMBH (DE) 2008-09-02 US claimed
EP-1441002-B1 PRE-EXPANDED POLYPROPYLENE RESIN BEAD AND MOLDED OBJECT OBTAINED THEREFROM BY IN-MOLD FOAMING KANEKA CORP (JP) 2008-03-26 EP claimed
EP-0909399-B1 RADIATION CURABLE RESIN COMPOSITION DSM NV (NL) 2002-10-02 EP claimed
US-6130270-A FOR OPTICAL PARTS SUCH AS LENSES, OPTICAL DISKS, PRISMS, LENS SHEETS WHICH ARE MOLDED BY POLYMERIZATION IN DIES; FOR USE AS SURFACE COATING MATERIAL OF PLASTIC FILM SUBSTRATES USED FOR OPTICAL MATERIALS SUCH AS FOR LIQUID CRYSTAL DISPLAY ELEMENTS DSM N.V. (NL) 2000-10-10 US claimed
EP-0909399-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1999-04-21 EP claimed
WO-1998001778-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1998-01-15 WO claimed
EP-0499188-B1 Polyoxazolidines with carbonate groups, process for their preparation and use thereof ENICHEM SPA (IT) 1996-10-09 EP claimed
EP-0499188-A1 Polyoxazolidines with carbonate groups, process for their preparation and use thereof ENICHEM SYNTHESIS S.p.A. (IT) 1992-08-19 EP claimed
US-4517315-A Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1985-05-14 US claimed
US-4234582-A Trialkyl isocyanates used as pesticides CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1980-11-18 US claimed
US-3980616-A Flameproofing agent for polyamide resins MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-09-14 US claimed