SCHEMBL24462575

SCHEMBL24462575

Cc1ccc2c(c1)oc1c(Br)cccc12

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
MAOB P27338 5/20 0.40
MAOA P21397 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
DYRK1A Q13627 1/20 0.38
CDC25A P30304 1/20 0.36
CDC25C P30307 1/20 0.36
POLB P06746 3/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPK1 P28482 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20116551 0.86 MAOB (0.43) KMT2AMEN1NPC1MAOBMAOA
SCHEMBL23433945 0.84 MAOA (0.40) KMT2AMEN1NPC1MAOBMAOA
SCHEMBL30829289 0.82 LOXL2 (0.41) KMT2AMEN1MAOALOXL2ALDH1A1
SCHEMBL3879946 0.82 LOXL2 (0.41) KMT2AMEN1MAOALOXL2ALDH1A1
SCHEMBL14565445 0.82 CYP1A2 (0.46) MAOBALDH1A1GAAHPGDDYRK1A
SCHEMBL13563983 0.81 MAOB (0.48) KMT2AMEN1NPC1MAOBALDH1A1
SCHEMBL13564024 0.80 DYRK1A (0.49) KMT2AMEN1MAOBMAOAALDH1A1
SCHEMBL21799297 0.79 MAOB (0.40) MAOBMAOALOXL2DYRK1ACDC25A
SCHEMBL20829181 0.79 MAOB (0.39) KMT2AMEN1NPC1MAOBMAOA
SCHEMBL24343646 0.79 DYRK1A (0.61) KMT2AMEN1MAOAALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4137488-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-02-22 EP disclosed
US-11345688-B2 Compound, preparing method therefor, and organic light emitting element comprising same DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2022-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345688-B2 Compound, preparing method therefor, and organic light emitting element comprising same CYP4F11, CYP4A11, WEE2 KMT2A 3112/4885MEN1 1059/4885NPC1 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.