SCHEMBL2446258

SCHEMBL2446258

Nc1ccc(Oc2ccc(C3(c4ccc(Oc5ccc(N)cc5C(F)(F)F)c(C(F)(F)F)c4)c4ccccc4-c4ccccc43)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
OPRK1 P41145 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PDK2 Q15119 13/20 0.43
POLB P06746 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
MAOA P21397 1/20 0.36
SCN9A Q15858 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2450314 0.94 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2441656 0.94 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2445421 0.92 ESR1 (0.45) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL29418332 0.92 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2439551 0.92 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL6138360 0.91 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL29418459 0.91 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2446597 0.90 MEN1 (0.51) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2446243 0.90 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2444878 0.90 KDM4E (0.51) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed