SCHEMBL6138360

SCHEMBL6138360

Nc1ccc(Oc2ccc(C3(c4ccc(Oc5ccc(N)cc5C(F)(F)F)c(-c5ccccc5)c4)c4ccccc4-c4ccccc43)cc2-c2ccccc2)c(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
OPRK1 P41145 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PDK2 Q15119 5/20 0.39
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
SCN9A Q15858 3/20 0.37
AR P10275 1/20 0.37
GLA P06280 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
PTGDR2 Q9Y5Y4 3/20 0.36
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418459 1.00 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25258809 0.92 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2446258 0.91 KDM4E (0.50) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25217980 0.89 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25218458 0.85 AR (0.38) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2445421 0.85 ESR1 (0.45) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2450314 0.85 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2441656 0.85 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2444878 0.83 KDM4E (0.51) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2443998 0.83 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0844283-B1 Curable resin composition and cured products JSR CORP (JP) 2002-10-09 EP claimed
US-6313233-B1 CAN BE CURED AND FABRICATED WITHOUT PRODUCING NO CRACKS INTO A CURED PRODUCT SUCH AS A SEMICONDUCTOR DEVICE HAVING A LOW DIELECTRIC CONSTANT, HIGH HEAT RESISTANCE AND MOISTURE RESISTANCE, SUPERIOR ADHESION TO VARIOUS SUBSTRATE MATERIALS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-06 US claimed
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
CN-114133590-A Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film 富士胶片商业创新有限公司 2022-03-04 CN disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-1117102-B1 Method of manufacturing material for forming insulating film JSR CORP (JP) 2005-08-10 EP disclosed
EP-0875906-B1 Electronic part and process for manufacturing the same JSR CORP (JP) 2004-04-07 EP disclosed
US-6642352-B2 Providing a silicon inorganic polymer compound or polyarylenes or polyphenylene ether organic polymer compound, treating the polymeric compound with a zeta-potential producing filter material, and producing curable polymer compound JSR CORPORATION (JP) 2003-11-04 US disclosed
EP-0844283-B1 Curable resin composition and cured products JSR CORP (JP) 2002-10-09 EP disclosed
US-6313233-B1 CAN BE CURED AND FABRICATED WITHOUT PRODUCING NO CRACKS INTO A CURED PRODUCT SUCH AS A SEMICONDUCTOR DEVICE HAVING A LOW DIELECTRIC CONSTANT, HIGH HEAT RESISTANCE AND MOISTURE RESISTANCE, SUPERIOR ADHESION TO VARIOUS SUBSTRATE MATERIALS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-06 US disclosed
US-20010009936-A1 Method of manufacturing material for forming insulating film JSR CORPORATION (JP) 2001-07-26 US disclosed
EP-1117102-A2 Method of manufacturing material for forming insulating film JSR Corporation (JP) 2001-07-18 EP disclosed
US-6084053-A AS STRUCTURAL COMPONENT, A DIELECTRIC POLYIMIDE MATERIAL HAVING AT LEAST ONE FLUORENE-CONTAINING STRUCTURAL UNIT; APPLYING POLYIMIDE SOLUTION TO SUBSTRATE, AND DRYING TO FORM THE DIELECTRIC; HEAT RESISTANCE, LOW DIELECTRIC CONSTANT JSR CORPORATION (JP) 2000-07-04 US disclosed
US-6011123-A ORGANOSILANE COMPOUND; POLYAMIC ACIDS HAVING A HYDROLYZABLE SILYL GROUP OR CARBOXYLIC ACID ANHYDRIDE GROUP, OR BOTH, AND POLYIMIDES HAVING A HYDROLYZABLE SILYL GROUP OR CARBOXYLIC ACID ANHYDRIDE GROUP, OR BOTH. JSR CORPORATION (JP) 2000-01-04 US disclosed
EP-0875906-A2 Electronic part and process for manufacturing the same JSR Corporation (JP) 1998-11-04 EP disclosed
EP-0844283-A1 Curable resin composition and cured products JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-27 EP disclosed