Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA3 | P07451 | 7/20 | 0.41 |
| ▸ | CA6 | P23280 | 7/20 | 0.41 |
| ▸ | CA7 | P43166 | 7/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.37 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463270 | 0.93 | CA1 (0.37) | KDM4EGAAMAPTCA1CA2 | |
| SCHEMBL30389971 | 0.93 | CA1 (0.37) | KDM4EGAAMAPTCA1CA2 | |
| SCHEMBL24463661 | 0.82 | — | — | |
| SCHEMBL24463568 | 0.80 | GAA (0.41) | KDM4EGAAMAPTCA1CA2 | |
| SCHEMBL18583976 | 0.76 | MAPT (0.50) | KDM4EGAAMAPTCA1CA2 | |
| SCHEMBL20337719 | 0.72 | ROCK2 (0.39) | KDM4EGAAMAPTCA1CA2 | |
| SCHEMBL31149474 | 0.72 | ROCK2 (0.39) | KDM4EGAAMAPTCA1CA2 | |
| SCHEMBL24463540 | 0.72 | ALOX15 (0.36) | KDM4EGAAMAPTALDH1A1ALOX15 | |
| SCHEMBL24463483 | 0.72 | ROCK2 (0.45) | KDM4EGAAMAPTALOX15 | |
| SCHEMBL20349186 | 0.72 | GAA (0.46) | KDM4EGAAMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | KINNATE BIOPHARMA INC. (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | KDM4E 2742/4885GAA 427/4885MAPT 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.