Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463483 | 0.85 | ROCK2 (0.45) | ROCK2 | |
| SCHEMBL24463568 | 0.82 | GAA (0.41) | ROCK2 | |
| SCHEMBL24463661 | 0.81 | — | — | |
| SCHEMBL10175794 | 0.70 | ROCK2 (0.46) | ROCK2HDAC1HDAC2 | |
| SCHEMBL29525834 | 0.70 | ROCK2 (0.46) | ROCK2HDAC1HDAC2 | |
| SCHEMBL25334548 | 0.70 | PRKCI (0.35) | HDAC3HDAC1HDAC2 | |
| SCHEMBL20349186 | 0.67 | GAA (0.46) | ROCK2HDAC1HDAC2 | |
| SCHEMBL30657517 | 0.67 | GAA (0.46) | ROCK2HDAC1HDAC2 | |
| SCHEMBL20503054 | 0.67 | HDAC1 (0.38) | HDAC3HDAC1HDAC2 | |
| SCHEMBL18960381 | 0.67 | TDP1 (0.41) | HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | KINNATE BIOPHARMA INC. (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | ROCK2 253/4885HDAC3 1114/4885HDAC1 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.