SCHEMBL29525834

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10175794	1.00	ROCK2 (0.46)	ROCK2GAAMAPTKDM4EGLA
	SCHEMBL30657517	0.92	GAA (0.46)	ROCK2GAAMAPTKDM4EALOX15
	SCHEMBL20349186	0.92	GAA (0.46)	ROCK2GAAMAPTKDM4EALOX15
	SCHEMBL24463483	0.85	ROCK2 (0.45)	ROCK2GAAMAPTKDM4EGLA
	SCHEMBL31702342	0.85	ROCK2 (0.39)	ROCK2GAAMAPTKDM4EGLA
	SCHEMBL20337719	0.85	ROCK2 (0.39)	ROCK2GAAMAPTKDM4EGLA
	SCHEMBL25335478	0.85	ROCK2 (0.42)	ROCK2GAAMAPTKDM4EGLA
	SCHEMBL31149474	0.85	ROCK2 (0.39)	ROCK2GAAMAPTKDM4EGLA
	SCHEMBL24463568	0.78	GAA (0.41)	ROCK2GAAMAPTKDM4EALOX15
	SCHEMBL20353506	0.78	ROCK2 (0.35)	ROCK2GAAMAPTKDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.