SCHEMBL24463570

SCHEMBL24463570

Fc1cc2[nH]c(C(F)(F)F)nc2c(F)c1I

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CSNK2A1 P68400 2/20 0.46
▸ CSNK2A2 P19784 1/20 0.46
▸ CSNK2B P67870 1/20 0.46
▸ MAPT P10636 4/20 0.41
▸ POLB P06746 2/20 0.41
▸ GAA P10253 2/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ NPSR1 Q6W5P4 2/20 0.39
▸ KDM4E B2RXH2 5/20 0.38
▸ HPGD P15428 3/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ HTT P42858 2/20 0.38
▸ ALDH1A1 P00352 3/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24463564 0.76 MAPT (0.38) CSNK2A1CSNK2A2CSNK2BMAPTPOLB
SCHEMBL24463056 0.76 HTT (0.43) CSNK2A1MAPTPOLBKDM4EHPGD
SCHEMBL29176006 0.74 MAPT (0.51) CSNK2A1CSNK2A2CSNK2BMAPTPOLB
SCHEMBL25223628 0.72 OPRL1 (0.41) CSNK2A1CSNK2A2CSNK2BMAPTL3MBTL1
SCHEMBL24463565 0.72 KDM4E (0.35) CSNK2A1MAPTPOLBGAAL3MBTL1
SCHEMBL24463149 0.71 ALDH1A1 (0.39) MAPTPOLBHPGDALDH1A1PARP1
SCHEMBL2439652 0.70 CSNK2A1 (0.37) CSNK2A1HPGDALDH1A1CBFB
SCHEMBL21894108 0.69 MEN1 (0.63) CSNK2A1CSNK2A2CSNK2BMAPTPOLB
SCHEMBL29799710 0.67 KDM5A (0.43) CSNK2A1CSNK2A2CSNK2BMAPTPOLB
SCHEMBL31748505 0.66 CBFB (0.33) CSNK2A1MAPTPOLBGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1 LLC (US) 2025-10-30 — — US disclosed
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases KHORA SPV 1, LLC (US) 2025-06-17 — — US disclosed
CN-116057045-A Fibroblast growth factor receptor kinase inhibitors 金耐特生物制药公司 2023-05-02 — — CN disclosed
EP-4161656-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES Kinnate Biopharma Inc. (US) 2023-04-12 — — EP disclosed
US-20230078839-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1, LLC 2023-03-16 — — US disclosed
US-11345681-B1 Inhibitors of fibroblast growth factor receptor kinases KINNATE BIOPHARMA INC. (US) 2022-05-31 — — US disclosed
US-11345681-B1 Inhibitors of fibroblast growth factor receptor kinases KINNATE BIOPHARMA INC. (US) 2022-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases FGFR1, FGFR2, FGFR3 CSNK2A1 267/4885CSNK2A2 264/4885CSNK2B 255/4885
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES FGFR1, FGFR2, FGFR3 CSNK2A1 267/4885CSNK2A2 264/4885CSNK2B 255/4885
US-11345681-B1 Inhibitors of fibroblast growth factor receptor kinases FGFR1, FGFR2, FGFR3 CSNK2A1 267/4885CSNK2A2 264/4885CSNK2B 255/4885
US-20230078839-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES FGFR1, FGFR2, FGFR3 CSNK2A1 267/4885CSNK2A2 264/4885CSNK2B 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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