Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CBFB | Q13951 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463056 | 0.78 | HTT (0.43) | HPGDALDH1A1CBFBKDM4ECSNK2A1 | |
| SCHEMBL19884927 | 0.73 | OPRL1 (0.56) | OPRL1HPGDALDH1A1SMN1; SMN2CBFB | |
| SCHEMBL24463570 | 0.72 | CSNK2A1 (0.46) | HPGDALDH1A1SMN1; SMN2CBFBKDM4E | |
| SCHEMBL2439652 | 0.72 | CSNK2A1 (0.37) | HPGDALDH1A1CBFBCSNK2A1PTGS1 | |
| SCHEMBL3828091 | 0.70 | OPRL1 (0.60) | OPRL1HPGDALDH1A1SMN1; SMN2CBFB | |
| SCHEMBL24463149 | 0.70 | ALDH1A1 (0.39) | HPGDALDH1A1MAPTNPC1 | |
| SCHEMBL14502998 | 0.67 | OPRL1 (0.56) | OPRL1HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30389924 | 0.63 | MAPT (0.42) | HPGDALDH1A1SMN1; SMN2KDM4ECSNK2A2 | |
| SCHEMBL16089559 | 0.63 | MAPT (0.42) | HPGDALDH1A1SMN1; SMN2KDM4ECSNK2A2 | |
| SCHEMBL17073311 | 0.62 | HPGD (0.57) | OPRL1HPGDALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097187-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023097187-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023097189-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023097189-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |