Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23465953 | 0.77 | DYRK1A (0.37) | DYRK1ACHRM5TGFBR1 | |
| SCHEMBL23465762 | 0.73 | DYRK1A (0.37) | DYRK1ASCN5ACHRM5EGLN2TGFBR1 | |
| SCHEMBL23465764 | 0.73 | DYRK1A (0.44) | DYRK1ASCN5ACHRM5EGLN2TGFBR1 | |
| SCHEMBL23466113 | 0.73 | CHRM5 (0.37) | DYRK1ASCN5ACHRM5EGLN2 | |
| Hydrochloric Acid SCHEMBL31600427 | 0.72 | DYRK1A (0.42) | DYRK1ASCN5ACHRM5EGLN2 | |
| SCHEMBL31489336 | 0.67 | PIK3CG (0.38) | — | |
| SCHEMBL18077230 | 0.65 | SCN5A (0.47) | DYRK1ASCN5ACHRM5EGLN2TGFBR1 | |
| SCHEMBL1585961 | 0.65 | DYRK1A (0.47) | DYRK1ASCN5ACHRM5TGFBR1 | |
| SCHEMBL24463401 | 0.65 | TGFBR1 (0.38) | DYRK1ATGFBR1 | |
| SCHEMBL29655509 | 0.64 | TGFBR1 (0.46) | DYRK1ASCN5AEGLN2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KHORA SPV 1 LLC (US) | 2025-10-30 | — | — | US | disclosed |
| US-12331039-B2 | Inhibitors of fibroblast growth factor receptor kinases | KHORA SPV 1, LLC (US) | 2025-06-17 | — | — | US | disclosed |
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-4161656-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | Kinnate Biopharma Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| US-20230078839-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KHORA SPV 1, LLC | 2023-03-16 | — | — | US | disclosed |
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | KINNATE BIOPHARMA INC. (US) | 2022-05-31 | — | — | US | disclosed |
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | KINNATE BIOPHARMA INC. (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12331039-B2 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | DYRK1A 967/4885SCN5A 3875/4885CHRM5 4875/4885 |
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | FGFR1, FGFR2, FGFR3 | DYRK1A 967/4885SCN5A 3875/4885CHRM5 4875/4885 |
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | DYRK1A 967/4885SCN5A 3875/4885CHRM5 4875/4885 |
| US-20230078839-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | FGFR1, FGFR2, FGFR3 | DYRK1A 967/4885SCN5A 3875/4885CHRM5 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.