Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 8/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24862335 | 0.90 | KDR (0.44) | ROCK1ROCK2MEN1USP2LMNA | |
| SCHEMBL24464173 | 0.89 | NPC1 (0.50) | ROCK1ABL1BCRROCK2MEN1 | |
| SCHEMBL24740966 | 0.84 | CYP1A2 (0.43) | ROCK1ROCK2MEN1USP2LMNA | |
| SCHEMBL24862400 | 0.84 | SYK (0.45) | ROCK1ROCK2MEN1USP2LMNA | |
| SCHEMBL24464202 | 0.83 | ROCK2 (0.53) | ROCK1SRCROCK2MEN1CYP3A4 | |
| SCHEMBL24740943 | 0.82 | ABCG2 (0.52) | ROCK1ROCK2MEN1USP2LMNA | |
| SCHEMBL24862273 | 0.82 | ROCK2 (0.55) | ROCK1ROCK2MEN1USP2LMNA | |
| SCHEMBL24862663 | 0.82 | ROCK2 (0.64) | ROCK1ROCK2MEN1LMNACYP1A2 | |
| SCHEMBL24862317 | 0.82 | ROCK2 (0.45) | ROCK1ROCK2MEN1USP2LMNA | |
| SCHEMBL24464195 | 0.81 | USP2 (0.47) | ROCK1ROCK2MEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903618-B1 | RHO KINASE INHIBITORS | KADMON CORP LLC (US) | 2022-06-01 | — | — | EP | disclosed |