Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 11/20 | 0.68 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.68 |
| ▸ | SLC2A1 | P11166 | 7/20 | 0.49 |
| ▸ | SLC2A3 | P11169 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20661283 | 0.89 | ROCK2 (0.69) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL24464196 | 0.88 | ROCK2 (0.68) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL17038104 | 0.86 | ROCK2 (0.70) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL24353608 | 0.84 | ROCK2 (0.72) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL24353607 | 0.83 | ROCK2 (0.67) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL17038107 | 0.81 | ROCK2 (1.00) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL17038101 | 0.81 | ROCK2 (0.68) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL24464191 | 0.79 | ROCK2 (0.55) | ROCK2ROCK1SLC2A1SLC2A3HPGD | |
| SCHEMBL24862352 | 0.79 | ROCK2 (0.55) | ROCK2ROCK1SLC2A1SLC2A3HPGD | |
| SCHEMBL17038110 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1SLC2A1SLC2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903618-B1 | RHO KINASE INHIBITORS | KADMON CORP LLC (US) | 2022-06-01 | — | — | EP | disclosed |