Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 10/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 6/20 | 0.39 |
| ▸ | SLC2A3 | P11169 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24862352 | 0.91 | ROCK2 (0.55) | ROCK2ROCK1SLC2A1SLC2A3MEN1 | |
| SCHEMBL20661283 | 0.89 | ROCK2 (0.69) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL17038104 | 0.87 | ROCK2 (0.70) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL24464172 | 0.87 | ROCK2 (0.52) | ROCK2ROCK1LMNASLC2A1SLC2A3 | |
| SCHEMBL24464169 | 0.85 | ROCK2 (0.53) | ROCK2ROCK1LMNAHPGDHTT | |
| SCHEMBL24353608 | 0.85 | ROCK2 (0.72) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL15639228 | 0.82 | ROCK2 (0.80) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL24464197 | 0.79 | ROCK2 (0.68) | ROCK2ROCK1SLC2A1SLC2A3HPGD | |
| SCHEMBL24862354 | 0.77 | ROCK2 (0.69) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL17038099 | 0.75 | ROCK2 (0.70) | ROCK2ROCK1SLC2A1SLC2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903618-B1 | RHO KINASE INHIBITORS | KADMON CORP LLC (US) | 2022-06-01 | — | — | EP | disclosed |