Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.66 |
| ▸ | HTR2A | P28223 | 12/20 | 0.66 |
| ▸ | HTR7 | P34969 | 5/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.66 |
| ▸ | DRD1 | P21728 | 2/20 | 0.66 |
| ▸ | DRD4 | P21917 | 2/20 | 0.66 |
| ▸ | DRD5 | P21918 | 2/20 | 0.66 |
| ▸ | HTR1D | P28221 | 2/20 | 0.66 |
| ▸ | HTR1B | P28222 | 2/20 | 0.66 |
| ▸ | HTR2C | P28335 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | HRH1 | P35367 | 2/20 | 0.66 |
| ▸ | DRD3 | P35462 | 2/20 | 0.66 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.66 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14378106 | 1.00 | DRD2 (0.66) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL4263975 | 0.96 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL4273254 | 0.96 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Paliperidone Palmitate SCHEMBL1871384 | 0.96 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL24018542 | 0.96 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Paliperidone Palmitate SCHEMBL12415674 | 0.96 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Paliperidone Palmitate SCHEMBL18131955 | 0.96 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL7343354 | 0.96 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Hydrochloric Acid SCHEMBL9196896 | 0.96 | DRD2 (0.70) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL6881948 | 0.91 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4005555-A1 | METHODS FOR ENSURING RESUSPENSION OF PALIPERIDONE PALMITATE FORMULATIONS | Janssen Pharmaceutica NV (BE) | 2022-06-01 | — | — | EP | disclosed |